MITIGATION OF MYCOTOXIN CONTAMINATION IN BROILERS THROUGH A LIQUID SOLUTION BASED ON PHYTOGENICS: EFFECTS ON PERFORMANCE, AND HEPATIC GENE EXPRESSION

Insaf Riahi1, Annabel Prats1, Raquel Codina1, Eva León1 Óscar Castro1, Amrita K. Dhara2, Anirvid Sarkar2, Sudipto Haldar2, Sayantani Sihi Arora2.

1 Technical department, BIŌNTE Nutrition S.L., 43204 Reus, Spain.
2 Agrivet Research & Advisory P Ltd., 714 Lake Town, Block A, 700089 Kolkata, India

INTRODUCTION

Mycotoxin contaminated feed disrupts broiler physiology and performance, especially liver function as severely affects vital organs and animal antioxidant status, requiring the use of anti-mycotoxin solutions to counteract their effects. Solutions containing natural extracts with a high antioxidant capacity, are taking a stance as new nutritional strategies for the mitigation of mycotoxin’s detrimental effects in animal nutrition.

OBJECTIVE

The aim of the present study was to evaluate the potential benefits of a liquid solution (LS) containing phytogenics of grape and olive extracts (Vitis Vinifera and Olea Europaea), administered via drinking water, on performance and liver gene expression in broiler chickens exposed to a natural multi-contaminated diet by mycotoxins.

MATERIALS AND METHODS

RESULTS

CONCLUSIONS

The liquid anti-mycotoxins solution (LS) administrated via drinking water enhances all the growth parameters studied (P<0.05) and down-regulates the liver gene expression of NRF-2 and EPXH-1 (P<0.05). It can be concluded that the liquid antimycotoxin solution, which contains phytogenics from grape and olive extracts, significantly increases the performance and regulates the hepatic gene expression of broilers challenged by a multi-mycotoxin contaminated diet.