INTRODUCTION
Oxidative stress is an important mechanism of deoxynivalenol ( toxicity DON mycotoxin generates free radicals that disrupt the redox balance and induce DNA damage and apoptosis in the liver In this context, natural plant extracts have received a great deal of attention due to their powerful antioxidant capacity, among a wide range of beneficial health properties
OBJECTIVE
The aim of the present study was to evaluate the in vitro capacity of an anti mycotoxins agent that contains a combination of polyphenolic compounds from turmeric (curcumin) and milk thistle (silymarin) extracts to reduce the oxidative stress induced in hepatic cells by DON.
MATERIALS AND METHODS
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RESULTS
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CONCLUSIONS
The combination of curcumin and silymarin is a thermostable combination of natural extracts that provide effective antioxidant activity to alleviate the oxidative stress induced by DON in hepatic cells
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